In cancer, complex communities of interacting cell types form powerful signaling networks that shape tumorigenesis. To facilitate new opportunities for individualized cancer management and therapeutic intervention, powerful analytical methods are needed to identify spatially-defined tumor microenvironments and their associations with clinical outcome.
In this PSB 2023 workshop
, we will explore and highlight recent advances in computational biology
at the nexus of single cell spatial biology and precision cancer medicine
. The workshop will consist of five 30-minute talks on state-of-the-art computational methods for spatial biology analysis, each given by an expert in the field. There will also be a 30-minute forum for open discussion. Topics will include multiplexed imaging, spatial transcriptomics, and platform integration (e.g., alignment of single-cell and spatial transcriptomics), with an emphasis on basic and translational cancer research. Our goal is to stimulate new ideas, foster critical debate, and form new collaborations in this exciting and emerging research area.